Handbook of Neurotoxicology [electronic resource] : Volume II /
Neurotoxins-whether natural products that can provide valuable therapeutic agents and research reagents or human-generated pollutants-have recently attracted great scientific interest. In the Handbook of Neurotoxicology, Volumes I and II, many leading researchers and clinicians-all acknowledged experts-review in depth the status of research in key areas of current neurotoxicologic interest and examine the latest methodologies for in vivo assessment of a wide spectrum of agents exhibiting neurotoxicologic properties. This second volume of the Handbook focuses on the biologic effects of human-made toxins on the developing organism, and of drugs of abuse. Here are discussed the interpretation of neurotoxicity data, the art of risk assessment, and the manifestation of CNS insult during development. The drugs of abuse surveyed include cocaine, marijuana, the cannabinoids, and amphetamines. Also provided are state-of-the-art methods for the evaluation of neurotoxicant effects by both imaging and neurobehavioral assessment. Volume I concentrates on the biological effects of both human-made neurotoxins (pesticides, mercury, lead, zinc, and polytypic by-products of combustion and manufacture) and those of natural origin (microbial and animal toxins). Up-to-date and timely, the Handbook of Neurotoxicology, Volumes I and II, not only affords today's biomedical and clinical investigators a full panoply of knowledge in all the critical areas of current neurotoxicologic interest, but also illuminates the latest methodologies for assessing the effects of a broad spectrum of significant neurotoxicological agents.
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Format: | Texto biblioteca |
Language: | eng |
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Totowa, NJ : Humana Press : Imprint: Humana Press,
2002
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Subjects: | Medicine., Pharmacology., Biomedicine., Pharmacology/Toxicology., |
Online Access: | http://dx.doi.org/10.1007/978-1-59259-165-7 |
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Medicine. Pharmacology. Biomedicine. Pharmacology/Toxicology. Medicine. Pharmacology. Biomedicine. Pharmacology/Toxicology. Massaro, Edward J. editor. SpringerLink (Online service) Handbook of Neurotoxicology [electronic resource] : Volume II / |
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Neurotoxins-whether natural products that can provide valuable therapeutic agents and research reagents or human-generated pollutants-have recently attracted great scientific interest. In the Handbook of Neurotoxicology, Volumes I and II, many leading researchers and clinicians-all acknowledged experts-review in depth the status of research in key areas of current neurotoxicologic interest and examine the latest methodologies for in vivo assessment of a wide spectrum of agents exhibiting neurotoxicologic properties. This second volume of the Handbook focuses on the biologic effects of human-made toxins on the developing organism, and of drugs of abuse. Here are discussed the interpretation of neurotoxicity data, the art of risk assessment, and the manifestation of CNS insult during development. The drugs of abuse surveyed include cocaine, marijuana, the cannabinoids, and amphetamines. Also provided are state-of-the-art methods for the evaluation of neurotoxicant effects by both imaging and neurobehavioral assessment. Volume I concentrates on the biological effects of both human-made neurotoxins (pesticides, mercury, lead, zinc, and polytypic by-products of combustion and manufacture) and those of natural origin (microbial and animal toxins). Up-to-date and timely, the Handbook of Neurotoxicology, Volumes I and II, not only affords today's biomedical and clinical investigators a full panoply of knowledge in all the critical areas of current neurotoxicologic interest, but also illuminates the latest methodologies for assessing the effects of a broad spectrum of significant neurotoxicological agents. |
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Medicine. Pharmacology. Biomedicine. Pharmacology/Toxicology. |
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Massaro, Edward J. editor. SpringerLink (Online service) |
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Massaro, Edward J. editor. SpringerLink (Online service) |
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Massaro, Edward J. editor. |
title |
Handbook of Neurotoxicology [electronic resource] : Volume II / |
title_short |
Handbook of Neurotoxicology [electronic resource] : Volume II / |
title_full |
Handbook of Neurotoxicology [electronic resource] : Volume II / |
title_fullStr |
Handbook of Neurotoxicology [electronic resource] : Volume II / |
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Handbook of Neurotoxicology [electronic resource] : Volume II / |
title_sort |
handbook of neurotoxicology [electronic resource] : volume ii / |
publisher |
Totowa, NJ : Humana Press : Imprint: Humana Press, |
publishDate |
2002 |
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http://dx.doi.org/10.1007/978-1-59259-165-7 |
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AT massaroedwardjeditor handbookofneurotoxicologyelectronicresourcevolumeii AT springerlinkonlineservice handbookofneurotoxicologyelectronicresourcevolumeii |
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1756264819281887232 |
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KOHA-OAI-TEST:1814072018-07-30T23:01:54ZHandbook of Neurotoxicology [electronic resource] : Volume II / Massaro, Edward J. editor. SpringerLink (Online service) textTotowa, NJ : Humana Press : Imprint: Humana Press,2002.engNeurotoxins-whether natural products that can provide valuable therapeutic agents and research reagents or human-generated pollutants-have recently attracted great scientific interest. In the Handbook of Neurotoxicology, Volumes I and II, many leading researchers and clinicians-all acknowledged experts-review in depth the status of research in key areas of current neurotoxicologic interest and examine the latest methodologies for in vivo assessment of a wide spectrum of agents exhibiting neurotoxicologic properties. This second volume of the Handbook focuses on the biologic effects of human-made toxins on the developing organism, and of drugs of abuse. Here are discussed the interpretation of neurotoxicity data, the art of risk assessment, and the manifestation of CNS insult during development. The drugs of abuse surveyed include cocaine, marijuana, the cannabinoids, and amphetamines. Also provided are state-of-the-art methods for the evaluation of neurotoxicant effects by both imaging and neurobehavioral assessment. Volume I concentrates on the biological effects of both human-made neurotoxins (pesticides, mercury, lead, zinc, and polytypic by-products of combustion and manufacture) and those of natural origin (microbial and animal toxins). Up-to-date and timely, the Handbook of Neurotoxicology, Volumes I and II, not only affords today's biomedical and clinical investigators a full panoply of knowledge in all the critical areas of current neurotoxicologic interest, but also illuminates the latest methodologies for assessing the effects of a broad spectrum of significant neurotoxicological agents.1 Developmental Neurotoxicology: Testing and Interpretation -- 2 Manifestations of CNS Insult During Development -- 3 Developmental Neurotoxicity: What Have We Learnedfrom Guideline Studies? -- 4 Risk Assessment of Developmental Neurotoxicants -- 5 Electrophysiologic Evidence of Neural Injury or Adaptation in Cocaine Dependence -- 6 Addictive Basis of Marijuana and Cannabinoids -- 7 Dopamine and Its Modulation of Drug-Induced Neuronal Damage -- 8 NMDA Antagonist-Induced Neurotoxicity and Psychosis: The Dissociative Stimulation Hypothesis -- 9 Emerging Drugs of Abuse: Use Patterns and Clinical Toxicity -- 10 Mechanisms of Methamphetamine-Induced Neurotoxicity -- 11 Neurotoxic Effects of Substituted Amphetamines in Rats and Mice: Challenges to the Current Dogma -- 12 Studies of Neural Degeneration Indicate that Fasciculus Retroflexus Is a Weak Link in Brain for Many Drugs of Abuse -- 13 Microsensors Detect Neuroadaptation by Cocaine: Serotonin Released in Motor Basal Ganglia Is Not Rhythmicwith Movement -- 14 Impact of Intoxication: Structural and Functional Modificationsin the Brain Induced by Ethanol Exposure -- 15 Structural and Functional Neuroimaging of the Effects of Opioids -- 16 Structural and Functional Neuroimaging of the Effects of Cocaine in Human and Nonhuman Primates -- 17 Functional Neuroimaging of Cannabinoid Effects -- 18 Neuroimaging of MDMA-Induced Neurotoxicity -- 19 Tier 1 Neurological Assessment in Regulated Animal Safety Studies -- 20 Neurological Assessment: The Role of the Clinicianin Clinical Neurotoxicology -- 21 Human Neuropsychological Testing and Evaluation.Neurotoxins-whether natural products that can provide valuable therapeutic agents and research reagents or human-generated pollutants-have recently attracted great scientific interest. In the Handbook of Neurotoxicology, Volumes I and II, many leading researchers and clinicians-all acknowledged experts-review in depth the status of research in key areas of current neurotoxicologic interest and examine the latest methodologies for in vivo assessment of a wide spectrum of agents exhibiting neurotoxicologic properties. This second volume of the Handbook focuses on the biologic effects of human-made toxins on the developing organism, and of drugs of abuse. Here are discussed the interpretation of neurotoxicity data, the art of risk assessment, and the manifestation of CNS insult during development. The drugs of abuse surveyed include cocaine, marijuana, the cannabinoids, and amphetamines. Also provided are state-of-the-art methods for the evaluation of neurotoxicant effects by both imaging and neurobehavioral assessment. Volume I concentrates on the biological effects of both human-made neurotoxins (pesticides, mercury, lead, zinc, and polytypic by-products of combustion and manufacture) and those of natural origin (microbial and animal toxins). Up-to-date and timely, the Handbook of Neurotoxicology, Volumes I and II, not only affords today's biomedical and clinical investigators a full panoply of knowledge in all the critical areas of current neurotoxicologic interest, but also illuminates the latest methodologies for assessing the effects of a broad spectrum of significant neurotoxicological agents.Medicine.Pharmacology.Biomedicine.Pharmacology/Toxicology.Springer eBookshttp://dx.doi.org/10.1007/978-1-59259-165-7URN:ISBN:9781592591657 |