Preeclampsia, pregnancy-related hypertension, and breast cancer risk

Pregnancy conditions accompanied by high blood pressure, such as preeclampsia and pregnancy-related hypertension, have been associated with a lower risk of breast cancer in several epidemiologic studies. It is unknown whether length of gestation or multiple occurrence of these conditions alters the association with breast cancer. It is also unknown whether the inverse association between preeclampsia and breast cancer risk is modified by menopausal status at breast cancer diagnosis. Using data from a large, population-based case-control study of breast cancer conducted on Long Island, New York, during 1996-1997, the authors examined these questions among ever-parous women (1,310 cases and 1,385 controls) using multivariate logistic models. Preeclampsia was inversely associated with breast cancer (odds ratio = 0.7, 95% confidence interval: 0.5, 1.0); this association was even stronger among women who had multiple occurrences of preeclampsia (odds ratio = 0.3, 95% confidence interval: 0.1, 0.9).

Bibliographic Details

Main Authors:	Terry, Mary Beth, Perrin, Mary autor/a, Salafia, Carolyn M. autor/a, Zhang, Fang Fang autor/a, Neugut, Alfred I. autor/a
Format:	Texto biblioteca
Language:	eng
Subjects:	Preeclampsia, Cáncer de mama, Embarazo, Hipertensión,
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